Local favourite Thompson saved three match points before prevailing 5-7, 7-6 (6), 6-3 against Nadal, who was playing his first tournament after nearly a year out with a hip injury.
Caroline Garcia and Kristina Mladenovic recovered from a set down to beat Americans Coco Gauff and Jessica Pegula
Struggling Swiatek will open her campaign against Slovakian Rebecca Sramkova.
Jasmine Paolini is the first Italian player to reach the French Open final since doubles partner Sara Errani in 2012.
Images from the US Open women's singles second round matches, at Flushing Meadows, New York, on Wednesday.
Iga Swiatek's hopes of landing another 'Sunshine Double' ended in a 6-4, 6-2 fourth round loss to Ekaterina Alexandrova on Monday as the world number one joined third seed Coco Gauff in making an early exit from the Miami Open.
IMAGES from the French Open at Roland Garros, in Paris, France, on Wednesday.
Images from the US Open matches played at Flushing Meadows on Saturday
Naomi Osaka said using words like 'no education' and 'no class' to criticise a Black tennis player were among the worst things to say as the debate over a heated row between Taylor Townsend and Jelena Ostapenko raged on
Coco Gauff battled past Elina Svitolina in the Auckland Classic final on Sunday to retain her title.
'Every time I step onto this court I'm playing for history.'
Sabalenka looked bemused when an out call went against her to give Belgian Mertens the first service break and a 4-3 lead in the opening set of their quarter-final, and a check by umpire Miriam Bley confirmed the call.
The 15-year-old American phenom was forced to dig deep to become the youngest player since Anna Kournikova in 1996 to reach the third round
Iga Swiatek was the latest top player to suffer an upset loss in Montreal as the Wimbledon champion
Alexander Zverev rallied from a set down to beat defending champion Alexei Popyrin in Toronto and move into the semi-finals.
As the 2025 French Open looms, all eyes may be on reigning champions and top seeds - but lurking just beneath the surface are several players quietly building momentum, ready to crash the party in Paris. From seasoned champions finding renewed form to rising stars with something to prove, here are four dark horses who could shake up the women's singles draw at Roland Garros.
Ostapenko said on Instagram that her anger stemmed from Townsend's refusal to apologise for benefiting from a net cord -- when the American's shot clipped the net and stayed in play -- and accused her of being disrespectful.
Defending champion Jannik Sinner swept past Felix Auger-Aliassime 6-0, 6-2 on Thursday to reach the Cincinnati Open semi-finals, the world number one extending his hardcourt winning streak to 25 matches.
France's Boisson wins first WTA title in Hamburg
Novak Djokovic begins his hunt for a fifth Flushing Meadows crown when he meets Moldovan Radu Albot
Murray knocked out by Fritz in Washington
Four-times Grand Slam champion Alcaraz, who is gearing up to defend the French Open title later this month, fired off 24 winners in a strong performance to seal victory.
'I just don't want to face that hate again.'
In the evening session, men's third seed Alexander Zverev and women's fourth seed Jessica Pegula were forced off the court mid-match due to rain and the threat of lightning.
Electronic line calling systems were also affected by the power cut, the ATP said, while spectators shared pictures of dark hallways at the Manzanares Park Tennis Center.
Swiatek is on a remarkable 34-match winning streak On the other side, Gauff has developed into a solid claycourt player
Elena Rybakina powered into her first Cincinnati Open semi-final after stunning defending champion Aryna Sabalenka 6-1, 6-4 on Friday, while five-times Grand Slam champion Carlos Alcaraz recovered from a second-set blip to beat Andrey Rublev.
Here is what you need to know about the prize pot on offer at Wimbledon 2025, the third major of the year:
'It's sad that I'm here protesting the same thing that she did 50-plus years ago'
Mboko saved a match point against Kazakh ninth seed Rybakina in front of adoring home support
French Open champion Gauff is in line for a clash with fellow American Jessica Pegula.
Serena Williams showed glimpses of what lies in store for rivals this season
Andreeva bids for Paris glory after stellar start to season
Here is what you need to know about the prize pot on offer at the 2024 US
Naomi Osaka tumbled out of the Berlin Open first round on Tuesday
Iga Swiatek beat Czech 10th seed Marketa Vondrousova to reach the Cincinnati Open semi-finals.
American teenager Coco Gauff stunned top seed Kiki Bertens to advance to her maiden WTA semi-final with a 7-6(1), 6-4 victory at the Linz Open in Austria on Friday, then went back to her hotel to do her schoolwork.
'Right now I'm focused on going to sleep tonight and winning the next Uno match and then tomorrow we focus back on practice and then get ready for the quarter-finals.'
Navratilova, who is openly gay, said it was vital for sports stars to speak out.
Aryna Sabalenka showed nerves of steel and champion's resolve to defeat Elena Rybakina in their Berlin Open quarter-final on Friday, saving four match points in the final-set tiebreak.